HEVA Business Partner - Dupixent

Genzyme Corporation
Posted on


Executive / senior industry position

Reference Number


Job ID R2547159 Date posted 03/21/2020

Sanofi Genzyme has pioneered the development and delivery of transformative therapies for patients affected by rare and debilitating diseases for over 30 years. We accomplish our goals through world-class research, collaboration with the global patient community, and with the compassion and commitment of our employees.  With a focus on rare diseases, multiple sclerosis and onco-immunology, we are dedicated to making a positive impact on the lives of the patients and families we serve. Sanofi Genzyme's portfolio of transformative therapies, which are marketed in countries around the world, represent groundbreaking and life-saving advances in medicine.  Sanofi Genzyme employees benefit from the reach and resources of one of the world's largest pharmaceutical companies, with a shared commitment to improving the lives of patients.

Dupixent is the flagship of Sanofi Genzyme life changing immunology Franchise. It is currently being launched worldwide in Atopic Dermatitis, asthma and chronic rhinosinusitis with nasal polyps and has the ambition of becoming the treatment of choice for all T2 related disease thanks to his innovative mode of action. This portfolio in a product counts more than 15 indications currently being either in POC or PRE POC. 


The incumbent will be accountable for strategic oversight of Health Economic and Outcomes Research (HEOR) studies to support the value propositions of Sanofi Genzymeโ€™s Dupixent (and related products) for dermatology pipeline indications starting ph3 development before end of this year. 


  • He/She will Develop strategies and provides new ideas and concepts on how to move the program, product and/or therapeutic franchise forward
  • Set strategic evidence generation priorities and direction for assigned responsibilities and is able to incorporate this into appropriate corporate planning documents in full alignment with product / brand strategy and close collaboration with matrix teams: V&A leads, Medical, & HEVA teams
  • Take a leadership role in the development of relationships and continued advocacy with external advisors in appropriate therapeutic areas
  • Develop collaborative research relationships that provide data of value to decision makers
  • Leverage interactions to identify strategies that will improve the impact of research and build advocates for data
  • Ensures patients, providers, and HTA perspective are included in HEVA and clinical plans, via interaction with HTA bodies (i.e. early scientific advices, pre-submission consultations, etc.) in collaboration with V&A, project team and relevant regions/key affiliates
  • Interacts with senior level management providing high level strategies and long-term vision of assigned work
  • Coordinates execution of key HEVA activities in collaboration with expert functions (modelling, Pros, RWE), and regional / local HEVA when appropriate
  • Engages with affiliates to support reimbursement dossier submission and answering questions/ overcoming HTA body objections to support optimal reimbursement
  • Ensures feasibility of translating evidence generated into real world effectiveness and cost effectiveness arguments
  • Drives development of Core Value Dossier, from inception to dissemination and training to regions / affiliates
  • Serves as a resource to commercial organization in terms of pricing, positioning and reimbursement of products based on economic evaluations
  • All incumbents are expected to demonstrate effective communication, organizational and interpersonal skills to be able to work effectively as part of a multidisciplinary team. 
  • The incumbent is expected to work independently, but in concert with the direction provided by their management, in accordance with defined functional policies and precedents, budgetary guidelines, company values, ethics and applicable law.



Responsible for the design of a HEVA Communication/Publication Plan with the objective to communicate the unique attributes of Dupixent to external multi-stakeholders to ensure the drugโ€™s value proposition will be recognized and hence market access and market uptake will be maximized

Key Performance Indicators:

  • Demonstrated contribution to product success
  • Development and execution of HEVA strategies and tactics that address data gaps and fulfill customer needs
  • Proactive communication and alignment with cross-functional stakeholders 
  • Strong ability to partner with the project teams and develop/present HEOR strategies and options
  • Recognized scientific expertise and influence within cross-functional teams
  • Established track record of scientific publications in peer reviewed journals
  • Compliance with all relevant internal SOPs


  • Advanced degree (PhD, MD, MS, MPH, or PharmD) in a scientific discipline
  • Clinical background should be supplemented with advanced quantitative training demonstrated by an MPH or MS in a relevant field
  • Minimum of 7 years of combined experience in health economics, outcomes research, or directly market access field
  • Immunology experienced preferred
  • Track record of publications in peer-reviewed journals demonstrating experience in PROs, observational research, and/or health economics
  • Thorough knowledge of global HTA processes and guidelines. Direct experience in making submissions to relevant payers and interacting with them is strongly desired (in US & Europe as a minimum).
  • Strong ability to partner with the business unit colleagues 
  • Demonstrated capabilities to develop global strategic HEVA plans and execute studies
  • Documented training in Health Economics desired
  • Proficiency in providing input into clinical trials
  • Experience with patient reported outcomes
  • Strong ability to partner with the business unit colleagues
  • Capabilities in develop global strategic HEVA plans and execute studies
  • Documented training in Health Economics desired
  • Proficiency in input into clinical trials and PROs knowledge preferred

Skills & Competencies:

  • English fluent, both written and oral
  • Strong communication skills, both verbal and written, including presentation skills essential. Significant experience making presentations to senior management is strongly desired
  • Strong ability to partner with the business and develop/present HEVA strategies and options
  • Results oriented and excellent analytic and collaboration skills
  • Broad knowledge of Health economics and Outcomes research methodology
  • Comprehensive understanding of clinical development strategies and trial designs
  • Understanding of medical and statistical scientific methodology
  • In-depth understanding of the legal and regulatory environment of the pharmaceutical industry, demonstrated integrity on work-related compliance considerations and solid ethics
  • Entrepreneurial and team spirit and ability to develop creative solutions to complex problems
  • Ability to manage complexity and ambiguity in a highly matrixed work environment
  • Self-motivated, acts autonomously and prioritize

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.



At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

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More Information

Posted on


Executive / senior industry position

Reference Number



Cambridge , United States